How to Rejuvenate Your Skin

By Dr. John H. Maher
updated 12 months ago

article reproduced from RxforWellness.com

Pregnenolone and DHEA are hormone precursors found in many organs, including skin, which will ultimately be converted into testosterone, estrone, and estradiol (1).* Studies indicate men and women produce less pregnenolone and DHEA as they age, thereby decreasing the amount available to the epidermis (outer layer of skin). This ultimately leads to diminished skin elasticity, firmness and moisture content (2,3).* Current work has revealed the existence of the enzyme systems required for normal biochemical conversion and regulation of epidermal estrogens. This is a state of the art, non-greasy, rapidly absorbed moisturizing cream that is quick drying and provides the skin with essential re-hydrating components.

Goldzieher reported increases in epidermis thickness along with a more orderly cell arrangement, elastic fibrils, capillary beds and water content when skin was exposed to topical estrogens (5).* Blau and Kanof noticed similar effects with the estrogen precursor pregnenolone(4).* Normal cellular metabolism, ultraviolet exposure (UV-A and UV-B), chemical solvents and environmental toxins have been shown to produce skin damaging free radicals. Alpha-lipoic acid (ALA), a unique fat and water-soluble antioxidant coupled with a patented liposomal preparation containing vitamin C, vitamin E (Oxysomes™). This liposomal preparation of proanthocyanidins extracted from grape seeds produce a powerful line-up against the harmful free radicals.

Alpha-lipoic acid (ALA) is a potent thiol antioxidant that has shown the potential to protect the skin (10).* The distinctive structure of ALA and liposomes provides enhanced transport across skin layers and cell membranes, while their water and lipid solubility allows effective free radical quenching both inside and outside the cell. This symbiotic relationship is further enhanced by ALA's ability to regenerate glutathione (6)* and various antioxidants like vitamin C and vitamin E, which have been shown to protect against skin damage (9)*, making for the ultimate in free radical eradication.

Furthering this "high-tech" formula is the inclusion of Borage Oil via a patented surfactant-free micro-emulsion chosen as the base of this cream. With patented European compounds, this formula was designed to minimize water loss and enhance quick drying without any noticeable oiliness, residue or "tackiness".

This moisturizing cream contains a highly purified grape seed extract containing a 95% oligomeric proanthocyanidin complex that has undergone several laboratory tests to validate its ability to protect the skin from free radical damage. This combination helps restore damaged collagen and elastin to its most resilient functional form (8). Collagen is the primary component of the inside layer of skin (dermis) while elastin gives the skin its strength, smoothness and elasticity.

Progesterone acts as a holding point or bond for sealing the cross points of collagen and elastin, similar to how cement holds bricks together in a brick wall. To remove wrinkles from the surface of the skin, we need collagen, elastin and the binding effects of progesterone.

These statements have not been evaluated by the Food & Drug Administration (FDA). This product is not intended to diagnose, cure, treat or prevent any disease.

References:

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J Am Acad Dermatol. 18:714, 1988.
Planta Medica. 57:38, 1991.
Biochem Pharmacol. 33:3933, 1984.
J Am Acad Dermatol.. 38: 45, 1998.
Biochem Pharmacol. 52: 627, 1996